Assessing the Candida in Healthy Subjects and Subjects with Oral Submucous Fibrosis: A Comparative Clinical Study

One precancerous condition with a high potential to turn into malignancy and pose risk is OSMF (oral submucous fibrosis) which mainly affects the young subjects globally as well in India. The etiology of attributed gutkha chewing habit. Another predominant etiologic factor governing etiopathogenesis malignant premalignant lesions Candida species. Our aim present clinical study was conducted assess compare intensity incidence species healthy oral fibrosis. This included 24 controls confirmed diagnosis OSMF. A detailed history recorded examination done for all subjects. All samples were obtained from rinse cultured using Sabouraud’s agar medium followed by identification counting isolated yeast on sugar assimilation test, chlamydospore formation, germ tube test. In group, 41.66% (n=10) However, control 16.66% (n=4) collected samples. difference showed that higher group compared (p=0.07). CFU/ml had range 500-970 mean CFU values 721.27±143.88. 60-320, whereas, value 186.64±130.10. group. statistically significant p-value 0.005. concludes C. Albicans, candida controls, however, these normal 3% 47%. Hence, cannot be considered an transforming lesion. further evaluation needed evaluate if betel quid promotes or inhibits invasion adherence